Gene network and familial analyses uncover a gene network involving Tbx5/Osr1/Pcsk6 interaction in the second heart field for atrial septation
نویسندگان
چکیده
منابع مشابه
Gene-gene Interaction Analyses for Atrial Fibrillation
Atrial fibrillation (AF) is a heritable disease that affects more than thirty million individuals worldwide. Extensive efforts have been devoted to the study of genetic determinants of AF. The objective of our study is to examine the effect of gene-gene interaction on AF susceptibility. We performed a large-scale association analysis of gene-gene interactions with AF in 8,173 AF cases, and 65,2...
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اندیشمندان و صاحب نظران علوم اجتماعی بر این باورند که مرحله تازه ای در تاریخ جوامع بشری اغاز شده است. ویژگیهای این جامعه نو را می توان پدیده هایی از جمله اقتصاد اطلاعاتی جهانی ، هندسه متغیر شبکه ای، فرهنگ مجاز واقعی ، توسعه حیرت انگیز فناوری های دیجیتال، خدمات پیوسته و نیز فشردگی زمان و مکان برشمرد. از سوی دیگر قدرت به عنوان موضوع اصلی علم سیاست جایگاه مهمی در روابط انسانی دارد، قدرت و بازتولید...
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Two types of distinct cardiac progenitor cell populations can be identified during early heart development: the first heart field (FHF) and second heart field (SHF) lineage that later form the mature heart. They can be characterized by differential expression of transcription and signaling factors. These regulatory factors influence each other forming a gene regulatory network. Here, we present...
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Introduction: Cardiovascular diseases are one of the leading causes of mortality in today’s industrial world. Occlusion of left atrial appendage (LAA) using the manufactured devices is a growing trend. The objective of this study was to develop a computer-aided diagnosis system for the identification of LAA in echocardiographic images. Method: The data used in this descriptive analytical study ...
متن کاملSegmentation of the Left Atrial Appendage in the Echocardiographic Images of the Heart Using a Deep Neural Network
Introduction: Cardiovascular diseases are one of the leading causes of mortality in today’s industrial world. Occlusion of left atrial appendage (LAA) using the manufactured devices is a growing trend. The objective of this study was to develop a computer-aided diagnosis system for the identification of LAA in echocardiographic images. Method: The data used in this descriptive analytical study ...
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ژورنال
عنوان ژورنال: Human Molecular Genetics
سال: 2016
ISSN: 0964-6906,1460-2083
DOI: 10.1093/hmg/ddv636